Suppression of Classical and Quantum Radiation Pressure Noise via Electro-Optic Feedback

We present theoretical results that demonstrate a new technique to be used to improve the sensitivity of thermal noise measurements: intra-cavity intensity stabilisation. It is demonstrated that electro-optic feedback can be used to reduce intra-cavity intensity fluctuations, and the consequent radiation pressure fluctuations, by a factor of two below the quantum noise limit. We show that this is achievable in the presence of large classical intensity fluctuations on the incident laser beam. The benefits of this scheme are a consequence of the sub-Poissonian intensity statistics of the field inside a feedback loop, and the quantum non-demolition nature of radiation pressure noise as a readout system for the intra-cavity intensity fluctuations.Comment: 4 pages, 1 figur

Effect of electrolyzed high-pH alkaline water on blood viscosity in healthy adults.

BACKGROUND: Previous research has shown fluid replacement beverages ingested after exercise can affect hydration biomarkers. No specific hydration marker is universally accepted as an ideal rehydration parameter following strenuous exercise. Currently, changes in body mass are used as a parameter during post-exercise hydration. Additional parameters are needed to fully appreciate and better understand rehydration following strenuous exercise. This randomized, double-blind, parallel-arm trial assessed the effect of high-pH water on four biomarkers after exercise-induced dehydration. METHODS: One hundred healthy adults (50 M/50 F, 31 ± 6 years of age) were enrolled at a single clinical research center in Camden, NJ and completed this study with no adverse events. All individuals exercised in a warm environment (30 °C, 70% relative humidity) until their weight was reduced by a normally accepted level of 2.0 ± 0.2% due to perspiration, reflecting the effects of exercise in producing mild dehydration. Participants were randomized to rehydrate with an electrolyzed, high-pH (alkaline) water or standard water of equal volume (2% body weight) and assessed for an additional 2-h recovery period following exercise in order to assess any potential variations in measured parameters. The following biomarkers were assessed at baseline and during their recovery period: blood viscosity at high and low shear rates, plasma osmolality, bioimpedance, and body mass, as well as monitoring vital signs. Furthermore, a mixed model analysis was performed for additional validation. RESULTS: After exercise-induced dehydration, consumption of the electrolyzed, high-pH water reduced high-shear viscosity by an average of 6.30% compared to 3.36% with standard purified water (p = 0.03). Other measured biomarkers (plasma osmolality, bioimpedance, and body mass change) revealed no significant difference between the two types of water for rehydration. However, a mixed model analysis validated the effect of high-pH water on high-shear viscosity when compared to standard purified water (p = 0.0213) after controlling for covariates such as age and baseline values. CONCLUSIONS: A significant difference in whole blood viscosity was detected in this study when assessing a high-pH, electrolyte water versus an acceptable standard purified water during the recovery phase following strenuous exercise-induced dehydration

Patterns of Pathogenesis: Discrimination of Pathogenic and Nonpathogenic Microbes by the Innate Immune System

The dominant conceptual framework for understanding innate immunity has been that host cells respond to evolutionarily conserved molecular features of pathogens called pathogen-associated molecular patterns (PAMPs). Here, we propose that PAMPs should be understood in the context of how they are naturally presented by pathogens. This can be experimentally challenging, since pathogens, almost by definition, bypass host defense. Nevertheless, in this review, we explore the idea that the immune system responds to PAMPs in the context of additional signals that derive from common “patterns of pathogenesis” employed by pathogens to infect, multiply within, and spread among their hosts

Hybrid procedure of bilateral pulmonary artery banding and bilateral ductal stenting in an infant with aortic atresia and interrupted aortic arch

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/109582/1/ccd25424.pd

CD-ROM preparation: An overview and guide

A primer on the options and procedures involved in producing CD-ROM products in a small to medium sized business operation is presented in language that persons with a minimal technical background can easily understand. The capabilities, limitations, and standards of CD-ROM technology are surveyed. Emphasis is placed on CD-ROM production, especially upon design, data conversion to an electronic medium, data file preparation, the use of vendors, and the steps for in-house production of CD-ROM products

Secure quantum key distribution using squeezed states

We prove the security of a quantum key distribution scheme based on transmission of squeezed quantum states of a harmonic oscillator. Our proof employs quantum error-correcting codes that encode a finite-dimensional quantum system in the infinite-dimensional Hilbert space of an oscillator, and protect against errors that shift the canonical variables p and q. If the noise in the quantum channel is weak, squeezing signal states by 2.51 dB (a squeeze factor e^r=1.34) is sufficient in principle to ensure the security of a protocol that is suitably enhanced by classical error correction and privacy amplification. Secure key distribution can be achieved over distances comparable to the attenuation length of the quantum channel.Comment: 19 pages, 3 figures, RevTeX and epsf, new section on channel losse

Protecting the Upper Chesapeake Bay: Fort Hollingsworth (1813-1815), Elk River, Cecil County, Maryland

Fort Hollingsworth, erected in April 1813 by the citizens of Cecil County, Maryland, was a small breastwork that protected the upper reaches of the Chesapeake Bay and the “backdoor” to Philadelphia during the War of 1812. Fort Hollingsworth saw brief action in 1814. After the war, it was demolished and the land returned to farming. Geophysical surveying, exploratory soil borings, detailed topographic mapping, and focused excavation conducted by the Archeological Society of Maryland convincingly and economically identified the footprint of Fort Hollingsworth. Methodological considerations are here coupled with a discussion of vernacular fortifications and the implications that unconventional fortifications have for their archaeological discovery and recordation